PUBLICATIONS
2019
A Sharma, RN McLaughlin Jr, RS Basom, C Kikawa, M OhAinle, JS Yount. (2019) Macaque interferon-induced transmembrane proteins limit replication of SHIV strains in an Envelope-dependent manner.
2018
A Sharma, J Overbaugh. (2018) CD4–HIV-1 Envelope Interactions: Critical Insights for the Simian/HIV/Macaque Model.
T Gobillot, D Humes, A Sharma, J Overbaugh. (2018) Lineage-dependent differences and the role of IFITM3 in the type-I interferon-induced restriction of Zika virus.
2017
John Nahabedian, Amit Sharma, Maryska E Kaczmarek, Greg K Wilkerson, Sara L Sawyer, Julie Overbaugh. (2017) Owl monkey CCR5 reveals synergism between CD4 and CCR5 in HIV-1 entry.
2016
DF Boyd, A Sharma, D Humes, C Cheng-Mayer, J Overbaugh. (2016) Adapting SHIVs In Vivo Selects for Envelope-Mediated Interferon-α Resistance.
Lei Feng, Venkatasubramanian Dharmarajan, Erik Serrao, Ashley Hoyte, Ross C Larue, Alison Slaughter, Amit Sharma, Matthew R Plumb, Jacques J Kessl, James R Fuchs, Frederic D Bushman, Alan N Engelman, Patrick R Griffin, Mamuka Kvaratskhelia. (2016) The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency.
Jacques J Kessl, Amit Sharma, Mamuka Kvaratskhelia. (2016) Methods for the Analyses of Inhibitor-Induced Aberrant Multimerization of HIV-1 Integrase.
2015
K Ronen, A Sharma, J Overbaugh. (2015) HIV Transmission Biology: Translation for HIV Prevention.
A Sharma, DF Boyd, J Overbaugh. (2015) Development of SHIVs with circulating, transmitted HIV‐1 variants.
NR Meyerson, A Sharma, GK Wilkerson, J Overbaugh, SL Sawyer. (2015) Identification of Owl Monkey CD4 Receptors Broadly Compatible with Early-Stage HIV-1 Isolates.
2014
Amit Sharma, Alison Slaughter, Nivedita Jena, Lei Feng, Jacques J Kessl, Hind J Fadel, Nirav Malani, Frances Male, Li Wu, Eric Poeschla, Frederic D Bushman, James R Fuchs, Mamuka Kvaratskhelia. (2014) A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase.
Sriram Aiyer, GVT Swapna, Nirav Malani, James M Aramini, William M Schneider, Matthew R Plumb, Mustafa Ghanem, Ross C Larue, Amit Sharma, Barbara Studamire, Mamuka Kvaratskhelia, Frederic D Bushman, Gaetano T Montelione, Monica J Roth. (2014) Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction.
Ross C Larue, Matthew R Plumb, Brandon L Crowe, Nikoloz Shkriabai, Amit Sharma, Julia DiFiore, Nirav Malani, Sriram S Aiyer, Monica J Roth, Frederic D Bushman, Mark P Foster, Mamuka Kvaratskhelia. (2014) Bimodal high-affinity association of Brd4 with murine leukemia virus integrase and mononucleosomes.
2013
Amit Sharma, Ross C Larue, Matthew R Plumb, Nirav Malani, Frances Male, Alison Slaughter, Jacques J Kessl, Nikolozi Shkriabai, Elizabeth Coward, Sriram S Aiyer, Patrick L Green, Li Wu, Monica J Roth, Frederic D Bushman, Mamuka Kvaratskhelia. (2013) BET proteins promote efficient murine leukemia virus integration at transcription start sites.
Lei Feng, Amit Sharma, Alison Slaughter, Nivedita Jena, Yasuhiro Koh, Nikolozi Shkriabai, Ross C Larue, Pratiq A Patel, Hiroaki Mitsuya, Jacques J Kessl, Alan Engelman, James R Fuchs, Mamuka Kvaratskhelia. (2013) The A128T Resistance Mutation Reveals Aberrant Protein Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors.
Chia-Yen Chen, Xiang Liu, Kathleen Boris-Lawrie, Amit Sharma, Kuan-Teh Jeang. (2013) Cellular RNA helicases and HIV-1: Insights from genome-wide, proteomic, and molecular studies.
2012
Amit Sharma, Alper Yilmaz, Kim Marsh, Alan Cochrane, Kathleen Boris-Lawrie. (2012) Thriving under Stress: Selective Translation of HIV-1 Structural Protein mRNA during Vpr-Mediated Impairment of eIF4E Translation Activity.
Amit Sharma, Kathleen Boris-Lawrie. (2012) Determination of Host RNA Helicases Activity in Viral Replication.
2010
Cheryl Bolinger, Amit Sharma, Deepali Singh, Lianbo Yu, Kathleen Boris-Lawrie. (2010) RNA helicase A modulates translation of HIV-1 and infectivity of progeny virions .